NIH plans to invite eligible US small businesses to apply for STTR grants (R41/R42) supporting collaborative research and technology development, with clinical trials not allowed.
Funder: National Institutes of Health
Due Dates: April 5, 2027
Funding Amounts: No specified ceiling; typical STTR Phase I/II awards vary by institute, generally up to $275,766 (Phase I) and $1,838,436 (Phase II) over 1–2 years.
Summary: Supports U.S. small businesses partnering with nonprofit research institutions to develop and commercialize innovative health-related technologies.
Key Information: Only U.S. small businesses (SBCs) are eligible; foreign entities are not eligible.
This opportunity supports the Small Business Technology Transfer (STTR) program, which enables United States small business concerns (SBCs) to collaborate with nonprofit research institutions in advancing scientific innovations toward commercialization. The grant funds feasibility studies as well as later-stage research and development projects needed to bring health-related products or services to market. The program is designed to foster technology transfer between research institutions and small businesses, promoting the development of new diagnostics, therapies, devices, and other innovations that address unmet health needs.