Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional)
This grant supports unique programs to address gaps in clinical research at designated hubs, with a focus on innovation and future scalability.
Funder: National Institutes of Health
Due Dates: March 13, 2025 | May 28, 2025 | September 29, 2025 | January 28, 2026 | May 28, 2026 | September 28, 2026 (all: application deadlines; letters of intent due 30 days prior)
Funding Amounts: Up to $500,000/year in direct costs (excluding consortium F&A); project period up to 5 years; number of awards depends on NIH appropriations.
Summary: Supports development and demonstration of unique hub capabilities, platforms, or resources to address critical gaps in clinical and translational science at awarded UM1 CTSA Program Hubs.
Key Information: Limited to primary UM1 CTSA hub institutions; applications must include required integration, milestones, and sustainability plans.
Description
This limited competition opportunity from the National Institutes of Health (NIH), administered by the National Center for Advancing Translational Sciences (NCATS), funds High Impact Specialized Innovation Programs (SIPs) at awarded UM1 Clinical and Translational Science Awards (CTSA) Program Hubs. The goal is to support the development and demonstration of unique hub capabilities, research platforms, and/or resources that address critical gap areas or roadblocks in clinical and translational science.
SIPs are intended to catalyze innovative, high-impact, and cross-cutting activities that can fundamentally enhance the research enterprise at CTSA UM1 hubs. Supported activities may include the creation of unique resources, transformative technologies, or platforms that benefit a wide range of clinical and translational science (CTS) projects. The program encourages projects in areas such as digital health, decentralized or pragmatic trials, AI/ML, clinical decision support, data science, real-world evidence, innovative trial designs, genomics, clinical informatics, biostatistics, community engagement, regulatory science, and telehealth.
Successful programs are expected to lay a strong foundation for future adoption and/or dissemination of these capabilities to additional CTSA Program Hubs.
