Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)
Funding opportunity to support specific pathogen-free macaque colonies for HIV/AIDS research by providing genetically characterized animals, free of certain viruses, essential for investigating the disease without confounding variables or risks to personnel.
Funder: National Institutes of Health
Due Dates: May 7, 2024 | September 7, 2024 | January 7, 2025 | May 7, 2025 | September 7, 2025 | January 7, 2026 | May 7, 2026 | May 25, 2026 | September 25, 2026
Funding Amounts: Application budgets are not limited but must reflect actual project needs; maximum project period is 4 years; prior approval required for $500,000+ direct costs in any year.
Summary: Supports continued maintenance and breeding of specific pathogen-free (SPF) macaque colonies for HIV/AIDS research, providing critical animal models to the research community.
Key Information: Only institutions previously funded under PAR-21-089 or PAR-18-669 are eligible to apply.
Description
This funding opportunity provides continued support for breeding and maintaining specific pathogen-free (SPF) macaque colonies that are essential for HIV/AIDS research. These colonies supply SPF macaques—free of certain confounding viruses and genetically characterized for major histocompatibility complex (MHC) class I types—to researchers investigating the pathobiology of HIV/AIDS, the development of new treatments and prevention strategies, and the impact of co-infections and co-morbidities. The program ensures a stable supply of high-quality, well-characterized macaque models for ongoing and future HIV/AIDS research efforts, with a focus on sustaining colony operations, rigorous viral testing, and comprehensive genetic typing.
