NIST Oligonucleotide Analysis by Mass Spectrometry
Develop mass spectrometry methods to analyze oligonucleotides and impurities for RNA-based healthcare, therapeutics, and vaccines.
This grant is no longer accepting proposals
NRC Research Associateship Programs has archived this opportunity.
Funder: NRC Research Associateship Programs
Due Dates: February 1, 2025 | May 1, 2025 | August 1, 2025 | November 1, 2025
Funding Amounts: Base stipend approximately $82,764/year with $3,000 travel allowance; typical appointment duration 2 years.
Summary: Postdoctoral fellowship to develop advanced mass spectrometry methods for oligonucleotide analysis supporting RNA-based healthcare, therapeutics, and vaccines at NIST.
Key Information: Open to U.S. citizens with a doctoral degree earned within the last 5 years; requires contacting a NIST Research Adviser prior to application.
Description
This fellowship opportunity at the National Institute of Standards and Technology (NIST) focuses on advancing analytical techniques in mass spectrometry for the characterization of oligonucleotides. The goal is to develop robust methods to detect, identify, and quantify oligonucleotides and their impurities in various forms, which is critical for the production of safe and consistent RNA-based products such as therapeutics and vaccines. The research supports biomanufacturing design and healthcare applications.
Available instrumentation includes high-resolution mass spectrometry platforms such as QToF, QExactive, Orbitrap, and quantitative triple quadrupole mass spectrometry (QQQ-MS) coupled with liquid chromatography. The program encourages applicants interested in contributing to this growing and impactful field.
Keywords associated with this opportunity include oligonucleotides, RNA, mass spectrometry, LC-MS/MS, therapeutics, vaccines, CRISPR-Cas, and mRNA.
