[National Institutes of Health](https://www.nih.gov/)

October 6, 2026 (Estimated)

R01 mechanism; award amounts and number of awards not yet specified.

Supports innovative research using machine learning, AI, and adaptive designs to enable personalized prevention/intervention strategies for cognitive and brain health in aging.

This is a forecasted opportunity; applications are not yet being accepted.

--- ## Description This upcoming funding opportunity from the National Institute on Aging (NIA) aims to support research that advances precision aging and cognitive health through the development or incorporation of novel study designs, methods, or analytic approaches. Emphasis is placed on leveraging machine learning, artificial intelligence, and adaptive designs to identify individual-level health and function profiles, ultimately facilitating personalized prevention plans and interventions for cognitive and brain health in older adults. Projects may span basic research in animal models to human studies, covering levels of analysis from cellular to societal. The opportunity will use the NIH R01 grant mechanism. --- ## Due Dates - Estimated Application Due Date: October 6, 2026 *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Funding mechanism: R01 (Research Project Grant) - Award ceiling, floor, and total program funding have not yet been specified. - Number of awards is not yet determined. --- ## Eligibility Eligible applicants include: - State, county, city, or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Private institutions of higher education - Native American tribal governments (Federally recognized and other) - Public housing authorities/Indian housing authorities - Nonprofits (with or without 501(c)(3) status), excluding institutions of higher education - For-profit organizations (including small businesses) - Eligible agencies of the Federal Government - U.S. territories or possessions - Faith-based or community-based organizations - Regional organizations - Non-domestic (non-U.S.) entities (foreign institutions) --- ## Application Process - This is a forecasted opportunity; applications are not currently being accepted. - Notice is provided to allow potential applicants time to develop collaborations and prepare responsive projects. - The official Notice of Funding Opportunity (NOFO) will be published closer to the estimated post date (August 2026). - Applications will be submitted through [Grants.gov](https://www.grants.gov/search-results-detail/360910) when the opportunity opens. --- ## Additional Information - The initiative encourages both basic and translational research, spanning animal models to human studies. - Projects should integrate advanced analytic techniques (AI, machine learning, adaptive designs) to enable individualized approaches to cognitive health in aging. - Investigators with relevant expertise are encouraged to begin planning and forming collaborations. --- ## External Links - [NIH/NIA Funder Page](https://www.nih.gov/) - [Opportunity Forecast on Grants.gov](https://www.grants.gov/search-results-detail/360910) --- ## Contact Information | Name | Email | Phone | |---------------------|------------------------------------|---------------| | Molly Wagster, Ph.D.| [wagsterm@nia.nih.gov](mailto:wagsterm@nia.nih.gov) | 301-496-9350 |

Novel Approaches to Advance Precision Aging and Cognitive Health

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