Novel Analytical Separation Science Methodology
This grant seeks to create new separation and detection methods for trace organic compounds in complex samples, with applications in environmental, clinical, and forensic fields.
This grant is no longer accepting proposals
NRC Research Associateship Programs has archived this opportunity.
Funder: NRC Research Associateship Programs
Due Dates: February 1, 2025 | August 1, 2025
Funding Amounts: Stipend approximately $82,764 per year plus $3,000 travel allowance; typical appointment duration 2 years.
Summary: Postdoctoral fellowship supporting innovative research in novel analytical separation and detection methods for trace organic compounds in complex natural matrices, with applications in environmental, clinical, nutritional, and forensic sciences.
Key Information: Open to U.S. citizens with a doctoral degree earned within the last 5 years; research conducted onsite at NIST in Gaithersburg, MD; requires prior contact with a Research Adviser.
Description
This postdoctoral research opportunity at the National Institute of Standards and Technology (NIST) focuses on developing novel analytical separation science methodologies. The research aims to create innovative approaches for the separation and detection of trace-level organic species in complex natural matrices. Key research topics include:
- Design, synthesis, and characterization of bonded stationary phases for liquid chromatography (LC), gas chromatography (GC), and supercritical fluid chromatography (SFC).
- Development of novel separation media and modes for electromigration techniques such as capillary electrophoresis (CE), capillary gel electrophoresis, micellar electrokinetic capillary chromatography, and capillary electrochromatography.
- Development and application of on-line multidimensional separation techniques based on orthogonal methodologies (e.g., LC-GC, LC-CE, LC-LC, GC-GC).
- Fast separation technologies in GC, LC, SFC, and CE.
- Application of existing separation modes in novel combinations, including chiral separations in SFC and CE.
- Design of new separation systems based on micellar and liposomal phases, antibody/antigen and receptor/ligand associations, and size-selective networks.
- Sensitive and selective detection systems for microcolumn separations, including mass spectrometry, laser-excited fluorescence, electrochemical, chemical reaction, and chemiluminescence approaches.
- Chromatographic and electrophoretic methods for measuring physicochemical properties such as octanol/water partition coefficients, aqueous solubilities, and vapor pressures.
The research emphasizes applications in environmental, clinical, nutritional, and forensic disciplines.
