Description

The Biomechanics and Mechanobiology (BMMB) program, part of the Mechanics of Materials cluster within NSF's Division of Civil, Mechanical, and Manufacturing Innovation, funds research that advances the understanding of engineering biomechanics and mechanobiology. The program emphasizes the study of biological mechanics from the sub-cellular to the whole-organism level, treating living tissues as smart, self-designing materials.

Projects must integrate both biological and mechanics components and aim to improve understanding of the mechanical behavior of living systems. The program welcomes investigations into the mechanical behavior of biological molecules, cells, tissues, and entire organisms. Key interests include the influence of in vivo mechanical forces on cell and matrix biology during tissue development, maintenance, regeneration, repair, and aging, as well as the translation of biomechanical discoveries into engineering science.

The program encourages, but does not require, multiscale mechanics approaches. Theoretical, computational, experimental, or combined methodologies are all eligible. While clinical trials are not supported, feasibility studies involving human or animal subjects may be considered if scientifically justified.

Proposals should clearly articulate the novelty and transformative potential of the work, its importance to engineering science, and its potential societal or industrial impact. Innovative proposals outside the core areas may be considered, but PIs are strongly encouraged to contact the program director before submission to ensure fit.