Parkinson's Disease Proteoforms Program
Funds projects generating high-resolution proteoform datasets from Parkinson’s brain and biofluids to accelerate biomarker discovery and advance understanding of disease biology.
Funder: Michael J. Fox Foundation for Parkinson's Research
Due Dates: July 21, 2026
Funding Amounts: Up to $1,000,000 per award; see program for details.
Summary: Supports research to generate high-resolution proteoform datasets from Parkinson’s brain and biofluids to advance biomarker discovery and understanding of Parkinson’s disease biology.
Description
The Parkinson's Disease Proteoforms Program funds projects that generate large-scale, high-resolution proteoform datasets from Parkinson's-relevant brain regions and matched biofluids. The program is structured around two tracks: (1) global proteoform profiling to systematically characterize disease-relevant molecular forms, and (2) tau proteoform characterization to advance understanding of tau biology in Parkinson's disease. Supported projects will produce detailed, annotated datasets to facilitate biomarker discovery, enable comparative analyses across disease stages and phenotypes, and integrate data for systems-level insights into Parkinson’s biology. All research outputs must comply with the foundation’s Open Science Policy, ensuring open sharing and accessibility.
