Parkinson's Disease Proteoforms Program
Funds research to generate high-resolution proteoform profiles from Parkinson's disease brain and biofluid samples to drive biomarker discovery and open data sharing.
Funder: Michael J. Fox Foundation for Parkinson's Research
Due Dates (Anticipated): October 2026 (Full application deadline, projected)
Funding Amounts: Award size and duration not specified; budget should be appropriate to the proposed scope and aligned with program goals.
Summary: Funds large-scale, high-resolution proteoform profiling in brain and biofluids to drive biomarker discovery and open data sharing for Parkinson's research.
Key Information: All research outputs must comply with MJFF's Open Science Policy for open and accessible data sharing.
Description
This program supports research to generate large-scale, high-resolution proteoform datasets from Parkinson's disease-relevant brain regions and matched biofluids. The aim is to advance biomarker discovery and enable the development of clinically meaningful, fluid-based biomarkers for Parkinson's disease. The program offers two complementary funding tracks:
- Global Proteoform Profiling: Broad, proteome-wide characterization of proteoforms, addressing gaps in conventional proteomics.
- Tau Proteoform Characterization: Focused studies on tau proteoforms relevant to Parkinson's disease.
Awardees will be provided with matched brain and biofluid samples. All research outputs, including data, code, and publications, must adhere to the foundation's Open Science Policy, ensuring open and accessible sharing.
