PCORI Call for Proposals for HSII Implementation Projects -- 2026 (HSII Participants Only)
PCORI funds HSII Participants to implement and evaluate evidence-based telepsychiatry or child weight management interventions in health systems using rigorous, stakeholder-engaged approaches.
Funder: Patient-Centered Outcomes Research Institute
Due Dates: April 28, 2026 (Letter of Intent, 5 pm ET) | September 1, 2026 (Full application, 5 pm ET)
Funding Amounts: Implementation Projects: up to $2.5M (201+ sites), $500K–$2M (fewer sites); Pilot Projects: up to $200K; max 48 months (Implementation), 24 months (Pilot)
Summary: Supports HSII Participants to implement and evaluate evidence-based care for telepsychiatry or healthy child weight management within their health systems.
Key Information: Open only to organizations with a fully executed HSII Master Funding Agreement (MFA) with PCORI.
Description
This funding opportunity from the Patient-Centered Outcomes Research Institute (PCORI) invites Health Systems Implementation Initiative (HSII) Participants to propose projects that promote the uptake of evidence generated from PCORI-funded patient-centered comparative clinical effectiveness research (CER) within their healthcare delivery settings. For the 2026 cycle, projects must focus on one of two evidence topics: (1) Telepsychiatry Collaborative Care for Complex Psychiatric Disorders, or (2) Family-Based Behavioral Treatment for Healthy Child Weight.
Applicants may propose either:
- HSII Implementation Projects: Broad efforts to integrate evidence-based interventions into care delivery to achieve sustainable, scalable practice change, with rigorous evaluation of both execution and impact on health and healthcare outcomes.
- HSII Pilot Projects: Smaller-scale efforts to develop and test implementation strategies, with the goal of demonstrating feasibility and readiness for broader implementation.
Projects must include robust program evaluation using the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, Maintenance) and engage relevant stakeholders, including patients and caregivers, throughout the process.
