Funder: Patient-Centered Outcomes Research Institute
Due Dates: May 13, 2025 (Letter of Intent) | September 3, 2025 (Full Application by invitation)
Funding Amounts: Up to $22 million total direct costs (Feasibility phase: up to $2M; Full-scale phase: up to $20M) over 6.5 years
Summary: Supports large-scale, two-phase randomized comparative effectiveness trials addressing critical healthcare decisions, requiring robust stakeholder engagement and shared leadership with a data coordinating center.
Key Information: Projects must include both a feasibility and full-scale phase; only multi-site randomized trials with meaningful engagement and a DCC are eligible.