This grant supports pilot studies to develop and test interventions or services for substance use and HIV prevention, requiring collaboration with stakeholders and a clear theory of change.
Funder: National Institutes of Health
Due Dates (Anticipated): October 2027 (Estimated application deadline) | October 2026 (Application deadline)
Funding Amounts: No cost sharing or matching required
Summary: Supports pilot and feasibility studies preparing for substance use and HIV intervention efficacy, effectiveness, or services research trials.
Key Information: Applicants must engage relevant end users in study design, execution, and interpretation; preliminary data are not required.
The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, supports pilot and feasibility studies preparing for efficacy, effectiveness, or services research trials. This R34 opportunity is clinical trial optional. Its scope includes interventions preventing substance use, misuse, or progression to disorder; prevention, treatment, and recovery services research, including comorbid pain and medical or mental health disorders; and HIV eradication research in substance use settings or populations.
Projects may address information gaps, strengthen stakeholder partnerships, or pilot test interventions. Supported activities include intervention development or adaptation, assessing intervention or service model acceptability and feasibility, and developing measures, materials, or methods for a future trial.