[National Institutes of Health](https://www.nih.gov)

November 17, 2025

Up to $295,924 per award; no minimum specified.

Supports small businesses developing technologies to address health-related social needs impacting substance use disorders (excluding alcohol use disorder).

--- ## Description This opportunity supports small business concerns (SBCs) in developing and commercializing innovative products or technologies that address the health-related social needs impacting substance use disorders (SUD), with the exception of alcohol use disorder. The aim is to promote solutions that can mitigate the social determinants contributing to SUD onset, progression, and recovery challenges. Technologies can be at any stage of development, provided there is a clear pathway toward commercialization and public health impact. --- ## Due Dates - Application Deadline: November 17, 2025 --- ## Funding Amount - Maximum award: $295,924 per project period - No minimum award specified - The number of awards is not specified - Cost sharing or matching is not required --- ## Eligibility - Only small businesses are eligible to apply. - Non-domestic (non-U.S.) entities and non-U.S. components of U.S. organizations are not eligible. - Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. - See the [full Notice of Funding Opportunity](http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-048.html) for additional eligibility details. --- ## Application Process - Applications must be submitted electronically via [Grants.gov](https://www.grants.gov/search-results-detail/350388). - Prepare your application according to the instructions in the official [funding announcement](http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-048.html). - Review Section VII of the announcement for agency contact information and additional submission details. --- ## Additional Information - This opportunity is part of the NIH Small Business Innovation Research (SBIR) program. - Projects must focus on health-related social needs as they pertain to SUD (excluding alcohol use disorder). - Technologies should be intended for commercialization and public health benefit. --- ## External Links - [NIH Funding Announcement (RFA-DA-25-048)](http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-048.html) - [Grants.gov Opportunity Listing](https://www.grants.gov/search-results-detail/350388) --- ## Contact Information | Contact | Email | Notes | |-------------------------|------------------------------|---------------------------------------------------------------------------------------------| | NIH Grants Information | grantsinfo@nih.gov | See Section VII. Agency Contacts within the full opportunity announcement for all inquiries. |

Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)

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