PTAC Research Grant
The Cystic Fibrosis Foundation's PTAC Research Grant funds research on innovative therapies and technologies to restore or repair CFTR function in cystic fibrosis, prioritizing gene editing and advanced delivery strategies.
Funder: Cystic Fibrosis Foundation
Due Dates (Anticipated): May 2027 (Full application deadline, projected)
Funding Amounts: Up to $150,000 per year plus 12% indirect costs for up to 2 years (total possible: $300,000 + indirects)
Summary: Supports research to develop and translate innovative therapies to restore or repair CFTR function in cystic fibrosis, as part of the Path to a Cure initiative.
Key Information: This is a forecasted opportunity; all dates are projected and subject to change.
Description
The Path to a Cure (PTAC) Research Grant, offered by the Cystic Fibrosis Foundation (CFF), supports research projects aimed at accelerating the development of therapies to restore cystic fibrosis transmembrane conductance regulator (CFTR) function in all patients with cystic fibrosis (CF). The program specifically targets foundational concepts, strategies, novel tools, methods, and technologies that could inform or translate into new therapies to restore CFTR protein function or repair/replace the defective CFTR gene. High-priority topics include gene insertion technologies, gene editing delivery, immune responses to genetic therapies, and in vitro efficacy and safety tools for CFTR restoration.
