Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
This grant funds a national research network to study how cancer and normal tissues respond biologically to radiation therapy, aiming to improve treatment and discover new therapy opportunities.
Funder: National Institutes of Health
Due Dates (Anticipated): January 2027 (Full application deadline, projected)
Funding Amounts: Cooperative agreement; award size and total program funding not yet specified; multi-year, multi-center support expected.
Summary: Supports collaborative research centers to advance translational studies on biological responses to radiation therapy in cancer patients.
Key Information: This is a forecasted opportunity; all dates and details are projected and subject to change.
Description
This opportunity, offered by the National Cancer Institute (NCI) at NIH, aims to continue support for the Radiation Oncology-Biology Integration Network (ROBIN). The program funds collaborative research centers (U54 mechanism, clinical trial required) to investigate the biological mechanisms underlying tumor and normal tissue responses to radiation therapy in cancer patients. ROBIN centers will conduct multidisciplinary, longitudinal studies, collecting and analyzing biospecimens and multimodal data before, during, and after standard-of-care radiation therapy. The goal is to reveal mechanisms of response, resistance, and toxicity, identify new therapy-induced targets, and determine whether initial treatment strategies remain optimal as therapy progresses. The network also aims to strengthen the radiation oncology workforce by integrating expertise across biology, clinical oncology, imaging, dosimetry, omics, biospecimen science, and data science, ultimately accelerating translational discoveries to inform future clinical trials and improve cancer outcomes.
