Request for Proposals: Biosecurity
Supports ambitious research and innovation to prevent and mitigate engineered biological threats, with a focus on biosecurity risks at the intersection of biotechnology and artificial intelligence.
Funder: Coefficient Giving
Due Dates: May 11, 2026: Expression of Interest (EOI) / applications close (deadline: 11:59pm PT)
Funding Amounts: Over $100 million expected to be awarded in 2026; both small grants and multi-year organizational grants available.
Summary: Supports ambitious projects to prevent and mitigate engineered biological threats, focusing on transmission suppression, technical safeguards, policy, and field-building.
Description
This opportunity from Coefficient Giving supports innovative projects that aim to prevent, detect, or respond to engineered biological threats, with a special focus on risks at the intersection of advanced biotechnology and artificial intelligence. The fund is open to a broad range of proposals, including those that address transmission suppression (such as scalable PPE and air disinfection), technical safeguards and governance (including AI-bio risk mitigation, synthesis screening, and misuse detection), policy and advocacy (educating decisionmakers and developing governance frameworks), and field-building (attracting and supporting talent in biosecurity). Projects that are ambitious, scalable, and have the potential for significant impact are especially encouraged.
The program welcomes applications from both new and previously funded teams or individuals. If your proposal does not neatly fit within the core categories but is highly aligned with catastrophic biosecurity risk mitigation, you are still invited to apply.
