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    Request for Proposals: Biosecurity

    Forecasted

    Request for Proposals: Biosecurity supports teams and individuals working on defenses, safeguards, policy, and field-building to prevent engineered biological threats and improve responses if prevention fails.

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    Funder: Coefficient Giving

    Due Dates (Anticipated): May 2027 (Expression of Interest deadline)

    Funding Amounts: Small grants for independent projects through multi-year organizational grants; biosecurity team expects to direct more than $100 million in 2026

    Summary: Supports teams and individuals preventing engineered biological threats and strengthening defenses, safeguards, policy, and field-building.

    Key Information: Open to academia, nonprofits, industry, and independent applicants, including previously funded teams and individuals.


    Description

    Coefficient Giving’s biosecurity team supports work to prevent engineered biological threats from emerging and improve responses if prevention fails. The program addresses accelerating risks from advances in AI and biotechnology, including mirror bacteria and viruses engineered with AI tools. It prioritizes rapid progress and concrete real-world outcomes, with support for ambitious teams and individuals.

    The four core priorities are transmission suppression, technical safeguards and governance, policy and advocacy, and field-building. Relevant work includes scalable respiratory protection and air disinfection, rigorous evaluations of dangerous AI capabilities, safeguards against biological misuse, gene synthesis screening, and governance of high-risk technologies. Fellowships, training, convenings, accelerators, and media can also receive support when they attract talent or strengthen work on catastrophic biological risks. Particularly aligned projects outside these priorities may be considered, but are less likely to receive funding.


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