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    Request for Proposals: Generic Drug Repurposing

    Supports late-stage clinical trials repurposing generic drugs to treat neglected, high-burden diseases in low- and lower-middle-income countries.

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    Funder: Coefficient Giving

    Due Dates: May 11, 2026 (Application deadline)

    Funding Amounts: Up to $20 million USD total; no maximum per proposal; multiple awards expected.

    Summary: Supports late-stage clinical trials repurposing generic drugs for neglected, high-burden diseases in low- and lower-middle-income countries.

    Key Information: Letters of interest required; open to global applicants with clinical research experience.


    Description

    This grant opportunity funds rigorous late-stage clinical trials investigating the repurposing of generic drugs for new indications, specifically targeting high-burden, neglected diseases affecting low- and lower-middle-income countries (LMICs). The initiative aims to accelerate patient access to effective, affordable treatments by leveraging the established safety profiles and supply chains of generic medicines. Coefficient Giving seeks to support research projects that can provide strong clinical evidence of efficacy for repurposed therapies where commercial incentives are lacking, ultimately addressing unmet medical needs in resource-limited settings.


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