[National Institutes of Health](https://www.nih.gov)

March 5, 2029

Up to $250,000 per award; estimated total program funding $2,500,000; approx. 10 awards expected.

Supports innovative research in clinical informatics to develop and advance methodologies and tools that improve health care delivery and outcomes.

No foreign subawards/subcontracts allowed; see eligibility for international collaboration details.

--- ## Description This opportunity from the National Library of Medicine (NLM) at NIH seeks applications for research in clinical informatics. The program aims to catalyze the development of novel informatics methodologies that enable clinicians, patients, and the public to better understand, manage, and improve health and health care delivery. Supported research should focus on designing, implementing, and evaluating tools and methods that facilitate data-driven discovery, evidence-based decision-making, and support personalized or precision healthcare. Emphasis is placed on scalable, domain-independent, and reproducible approaches for managing digital health objects such as electronic health records, clinical notes, imaging, and patient-generated data. Projects are expected to transform heterogeneous health data into actionable knowledge, accelerate scientific insights, improve clinical workflows, and lead to better health outcomes. --- ## Due Dates - March 5, 2029 --- ## Funding Amount - Maximum award per project: $250,000 - Estimated total program funding: $2,500,000 - Expected number of awards: 10 - No cost sharing or matching required --- ## Eligibility - Eligible applicants include: - State, county, city, or township governments - Special district governments - Independent school districts - Public and state-controlled institutions of higher education - Native American tribal governments (federally recognized and other tribal organizations) - Public housing authorities/Indian housing authorities - Nonprofits (with or without 501(c)(3) status, except those that are institutions of higher education) - Private institutions of higher education - For-profit organizations (including small businesses) - Others as specified in the NOFO - Foreign organizations and non-domestic (non-U.S.) entities are eligible to apply. - Non-domestic components of U.S. organizations are eligible. - Foreign components as defined by NIH policy are allowed. - **Important restriction:** NIH will not fund applications involving foreign subawards/subcontracts under this NOFO. All monetary international collaborations involving foreign subawards/subcontracts must respond to a NOFO specifically designated for international collaborations. Unfunded international collaborations, foreign consultants, or procurement of unique equipment/supplies from foreign vendors are permitted. --- ## Application Process - Submit applications through [Grants.gov](https://www.grants.gov/search-results-detail/359004). - Review Section III of the NOFO for detailed eligibility and requirements. - Prepare a proposal aligning with the program’s focus on innovative, scalable, and generalizable clinical informatics research. - Contact the program officer for clarifications if needed. --- ## Additional Information - No cost sharing or matching is required. - Projects should demonstrate potential for broad impact across clinical settings and populations. - Emphasis on reproducibility, scalability, and generalizability of informatics solutions. - Applications involving foreign subawards/subcontracts will be deemed noncompliant and not considered for funding. --- ## External Links - [NIH Funder Homepage](https://www.nih.gov) - [Official Grants.gov Listing](https://www.grants.gov/search-results-detail/359004) --- ## Contact Information | Contact | Email | Phone | |------------------------|------------------------------|---------------| | NLM Extramural Programs| NLMProgram@nih.gov | 301-496-4000 |

Research Grants in Clinical Informatics (R01 Clinical Trial Optional)

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