Grant Program - Coalition to Cure Calpain 3 supports researchers through calpainopathy research, tool development, and conference travel to advance treatments and clinical trial readiness.
Funder: Coalition to Cure Calpain 3
Due Dates: Rolling (Research Grant Letters of Intent)
Funding Amounts: Over $3 million committed to calpainopathy projects to date
Summary: Supports calpainopathy research, research tools, and investigator travel to advance treatments and clinical trial readiness for LGMD2A/R1 and LGMDD4.
Key Information: Research Grant payments depend on completion of predetermined milestones.
Coalition to Cure Calpain 3 (C3) supports scientific and clinical research to develop effective treatments and ultimately a cure for calpainopathy, including LGMD2A/R1 and LGMDD4. Led by Scientific Director Dr. Jennifer Levy, the program supports established scientists and clinicians as well as early-career investigators. Therapeutic priorities include gene therapy, gene editing, and non-genetic drug therapies, with the goal of bringing promising work to clinical trials.
C3 also invests in tools and clinical trial readiness: patient registries, natural history studies, outcome measures, animal models, and fundamental disease biology. Its research portfolio includes cell models and biomarkers. Alongside Research Grants, Travel Grants help investigators conducting calpainopathy research attend relevant conferences and meetings to present their work.