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    Research Program Award (R35 Clinical Trial Optional)

    Forecasted

    The NINDS Research Program Award (R35) offers longer-term, flexible funding for investigators to pursue neurological research, reduce administrative work, and mentor trainees, with applications not yet open.

    This grant is no longer accepting proposals

    National Institutes of Health has archived this opportunity.

    Funder: National Institutes of Health

    Due Dates (Anticipated): July 2027 (Full application deadline, projected) | July 2026 (Application deadline, projected)

    Funding Amounts: $350,000–$750,000 per year (typical range); multi-year support expected.

    Summary: Provides stable, flexible, multi-year funding to support long-term, innovative neuroscience research aligned with the NINDS mission.

    Key Information: This is a forecasted opportunity; application details and exact dates will be confirmed in the official NOFO.


    Description

    The National Institute of Neurological Disorders and Stroke (NINDS) is planning to offer a Research Program Award (R35, Clinical Trial Optional) to provide longer-term, flexible support for Program Directors/Principal Investigators (PDs/PIs) at most career stages. The goal is to reduce administrative burden and allow investigators to focus on high-impact neuroscience research, mentoring, and the pursuit of innovative ideas. This mechanism is intended for research directly aligned with the NINDS mission and is not suitable for projects primarily supported by other NIH Institutes or Centers.

    Key features of this award include:

    • Multi-year, stable funding to support ambitious, long-term research agendas.
    • Flexibility to pursue new research directions as opportunities arise, not limited to specific aims.
    • Reduced need for multiple concurrent grant applications.
    • More time for PDs/PIs to mentor the next generation of biomedical researchers.

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