Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)
Forecasted
CDC/ATSDR seeks research proposals to study and evaluate risk factors for ALS, including environmental, genetic, and population-specific factors, with funding for various research approaches and populations.
Funder: Centers for Disease Control and Prevention - ERA
Due Dates (Anticipated): February 2027 (Estimated application deadline)
Funding Amounts: Up to $500,000 per award; $4.5 million estimated total funding for 3 awards
Summary: CDC/ATSDR supports research identifying and evaluating environmental, genetic, and other potential risk factors for amyotrophic lateral sclerosis (ALS).
Key Information: Additional eligibility requirements will be included in the Notice of Funding Opportunity (NOFO).
Description
CDC/ATSDR invites research proposals to identify and evaluate potential risk factors for amyotrophic lateral sclerosis (ALS). The program encourages studies addressing military service, contact sports, traumatic brain injury, neuroinflammation, and infectious agents and exposures. Funding is offered through cooperative agreements across four research options.
The options span research grounded in strong existing evidence, exploratory studies of less-established risk factors or innovative methods, and investigations of ALS risk in affected populations, including military veterans. A fourth option focuses on biological samples from the Guamanian ALS cluster. That work may examine disease mechanisms, environmental factors, exposure routes, genetics, and biomarkers, with potential applications to mitigation, therapeutics, diagnostics, or prevention.
