[Coefficient Giving](https://coefficientgiving.org/apply-for-funding)

Rolling (unsolicited proposals accepted year-round)

Typical grants range from ~$50,000 to over $6 million; project duration and size vary by scope.

Supports high-impact, cost-effective biomedical and global health research in neglected, important, and tractable areas.

Highly competitive (1–2% of unsolicited proposals funded); focus is on neglected global health needs, not well-funded diseases.

--- ## Description Coefficient Giving funds biomedical and global health research projects that address significant, underfunded, and tractable challenges. The program is guided by strategic cause selection criteria—prioritizing importance (scale of impact), neglectedness (lack of sufficient funding relative to disease burden), and tractability (likelihood that additional funding can make a difference). The fund supports a wide range of projects, from computational protein design and vaccine development to diagnostics, implementation research, and market-shaping initiatives for neglected diseases. The overarching goal is to enable transformative advances in global health by supporting research that is often overlooked by traditional funders. --- ## Due Dates - Rolling: Proposals are accepted at any time. There are no fixed deadlines for unsolicited applications. --- ## Funding Amount - Grant sizes vary substantially, typically ranging from ~$50,000 (e.g., conference support) to over $6 million (e.g., major research initiatives). - Over $550 million has been awarded across 330+ grants since 2016. - Project duration and funding are tailored to the specific needs and scope of each project. --- ## Eligibility - Open to researchers, academic institutions, non-profit organizations, and other entities conducting biomedical or global health research. - Proposals must address problems that are: - Important: Affect large populations or have significant health/economic impact. - Neglected: Receive less funding relative to their global health burden. - Tractable: Where philanthropic support can realistically drive progress. - Areas less likely to be funded include: cancer, diabetes, reproductive medicine, rare diseases, pain, mental health, most HIV/AIDS work, and issues primarily affecting high-income countries. - Both invited and unsolicited proposals are considered, but unsolicited proposals are highly competitive (historical funding rate for unsolicited proposals is 1–2%). --- ## Application Process - Most grants are initiated by Coefficient Giving through proactive outreach, but unsolicited proposals are accepted. - To submit an unsolicited proposal: - Email [science@coefficientgiving.org](mailto:science@coefficientgiving.org) with: - A short description of an existing proposal submitted elsewhere, or - A new 1–2 page proposal including a rough budget and estimated timeline. - Only proposals that strongly align with program goals will receive a response. - For more details, see [the fund’s funding criteria page](https://coefficientgiving.org/funds/science-and-global-health-rd/our-funding-criteria) and [grantmaking process](https://coefficientgiving.org/our-approach/grantmaking-process/). --- ## Additional Information - The fund emphasizes “hits-based giving,” tolerating risk in pursuit of potentially transformative breakthroughs. - Supported research spans basic science, preclinical and clinical studies, diagnostics, implementation science, and market access. - Notable funded projects include computational vaccine design, malaria and hepatitis vaccine trials, nutrition interventions, and novel disease diagnostics. - For examples, see [portfolio highlights](https://coefficientgiving.org/research/five-highlights-from-our-scientific-research-portfolio/) and [recent grants](https://coefficientgiving.org/funds/science-and-global-health-rd/#grants-science-and-global-health-randd). --- ## External Links - [Science and Global Health R&D Fund Overview](https://coefficientgiving.org/funds/science-and-global-health-rd/) - [Our Funding Criteria](https://coefficientgiving.org/funds/science-and-global-health-rd/our-funding-criteria) - [Strategic Cause Selection](https://coefficientgiving.org/research/strategic-cause-selection/) - [Recent Grants List](https://coefficientgiving.org/funds/science-and-global-health-rd/#grants-science-and-global-health-randd) - [Grantmaking Process](https://coefficientgiving.org/our-approach/grantmaking-process/) - [Scientific Research Portfolio Highlights](https://coefficientgiving.org/research/five-highlights-from-our-scientific-research-portfolio/) --- ## Contact Information | Purpose | Contact | |--------------------|--------------------------------------------------------| | General inquiries | [Contact form](https://coefficientgiving.org/contact) | | Proposal submission| [science@coefficientgiving.org](mailto:science@coefficientgiving.org) | | Partnership | [partnerwithus@coefficientgiving.org](mailto:partnerwithus@coefficientgiving.org) |

Science and Global Health R&D

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