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    Science and Global Health R&D

    Science and Global Health R&D supports researchers and organizations developing biomedical research and new health tools to address neglected challenges and improve global health cost-effectively.

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    Funder: Coefficient Giving

    Due Dates:

    Funding Amounts: More than $550 million in grants and $100 million in social investments made across the portfolio

    Summary: Supports biomedical research and new tools offering exceptional opportunities for cost-effective improvements in global health.

    Key Information: Unsolicited proposals are considered, but historically only about 1–2% received funding.


    Description

    Coefficient Giving’s Science and Global Health R&D fund supports research and development into new tools to improve human health. It prioritizes important, neglected, and tractable biomedical challenges, particularly potentially high-impact projects overlooked by other funders. Neglectedness is assessed partly by comparing public and private research spending with disability-adjusted life year (DALY) burden. The fund is particularly interested in stalled products or fields where additional resources could accelerate breakthroughs.

    Its work spans transformative basic research and tool development, preclinical and clinical studies, implementation research, technical assistance, and market shaping. Examples include computational protein design, clean-water tools, late-stage malaria vaccine trials, and expanded access to sickle cell diagnostics and treatments. Grantmaking follows cause-selection criteria rather than fixed disease groups, product categories, or development phases, with cost-effectiveness as the common thread.


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