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    Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

    This program funds NIH-supported groups to buy or upgrade shared, state-of-the-art research instruments, aiming to boost collaboration and research impact, with awards from $300,000 to $5,000,000.

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    Funder: National Institutes of Health

    Due Dates: July 1, 2026 (estimated)

    Funding Amounts: $300,000–$5,000,000 per award; estimated total program funding $83M; up to 102 awards

    Summary: Supports purchase or upgrade of major shared-use research instruments to enhance biomedical research infrastructure.

    Key Information: Cost sharing is required for premium or special use instruments.


    Description

    The Shared Instrumentation Grant (SIG) Program provides funding for groups of NIH-supported investigators to acquire or upgrade a single item of state-of-the-art, commercially available research instrumentation or integrated instrumentation systems. This restructured program consolidates previous NIH instrumentation funding opportunities, aiming to improve access to advanced research tools, foster collaboration, and promote efficient, cost-effective research operations. Instruments must be optimally shared to benefit broad research communities, support rigorous and reproducible measurements, and encourage collaborative research.


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