[National Institutes of Health](https://www.nih.gov/)

July 1, 2026 (estimated)

$300,000–$5,000,000 per award; estimated total program funding $83M; up to 102 awards

Supports purchase or upgrade of major shared-use research instruments to enhance biomedical research infrastructure.

Cost sharing is required for premium or special use instruments.

--- ## Description The Shared Instrumentation Grant (SIG) Program provides funding for groups of NIH-supported investigators to acquire or upgrade a single item of state-of-the-art, commercially available research instrumentation or integrated instrumentation systems. This restructured program consolidates previous NIH instrumentation funding opportunities, aiming to improve access to advanced research tools, foster collaboration, and promote efficient, cost-effective research operations. Instruments must be optimally shared to benefit broad research communities, support rigorous and reproducible measurements, and encourage collaborative research. --- ## Due Dates - Estimated application due date: July 1, 2026 *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Award size: $300,000 (minimum) to $5,000,000 (maximum) per award - Estimated total program funding: $83,000,000 - Expected number of awards: 102 - No cap on the total cost of the instrument, but NIH contribution is capped at $5M per award - Cost sharing required for premium or special use instruments --- ## Eligibility Eligible applicants include: - Public and State controlled institutions of higher education - Private institutions of higher education - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Applicants must propose the purchase or upgrade of a single item of major, shared-use instrumentation that will be used by NIH-supported investigators. --- ## Application Process - Review the [grant opportunity on Grants.gov](https://www.grants.gov/search-results-detail/360532) - Prepare a proposal describing the need, intended users, and impact of the proposed instrumentation - Demonstrate institutional commitment to sharing and maintaining the instrument - Provide cost sharing plan if applying for premium or special use instruments - Submit application electronically via Grants.gov by the due date --- ## Additional Information - Clinical trials are not allowed under this funding opportunity. - The program is highly competitive; strong justification for the instrument’s necessity and broad user base is essential. - Applicants should review specific NIH instructions and requirements for instrumentation grants. --- ## External Links - [NIH Main Website](https://www.nih.gov/) - [Grant Opportunity on Grants.gov](https://www.grants.gov/search-results-detail/360532) --- ## Contact Information | Name | Email | Phone | |---------------------|---------------------------------------------|--------------| | Xiang-Ning Li, MD, PhD | [xiang-ning.li@nih.gov](mailto:xiang-ning.li@nih.gov) | 301-435-1744 |

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

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