Single Source: Chronic Kidney Diseases of Uncertain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Renal and Environmental Science Core (U01-Clinical Trial Not Allowed)
This grant supports research to uncover causes and risk factors of chronic kidney disease of uncertain origin in agricultural communities, aiming to improve prevention and treatment strategies.
Funder: National Institutes of Health
Due Dates (Anticipated): July 2026 (application deadline, projected)
Funding Amounts: Estimated total program funding: $1,750,000; 1 award expected; project duration and ceiling not specified.
Summary: Supports the Renal and Environmental Science Core of the CURE Consortium to advance research on the causes, mechanisms, and interventions for chronic kidney disease of uncertain etiology (CKDu) in agricultural communities.
Key Information: This is a forecasted, single-source opportunity; application(s) will be peer-reviewed and only funded if meritorious.
Description
This opportunity supports the continuation of the Consortium to Study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE), specifically funding the Renal and Environmental Science Core. CKDu is a form of kidney failure prevalent in rural areas of many low- and middle-income countries, particularly affecting young, working-age populations. Environmental factors, as well as potential genetic susceptibilities, are suspected contributors. The CURE Consortium, jointly funded by NIDDK, NIEHS, and FIC, aims to uncover the causes and potential interventions for CKDu, with implications for kidney health in the United States as well.
The Renal and Environmental Science Core will provide leadership and support for discovery science within the consortium, collaborating to maximize scientific opportunities, understand CKDu etiologies, identify exposures and therapeutic targets, and inform future public health interventions. The Consortium also serves as a resource for ancillary studies.
