Funder: National Institutes of Health
Due Dates: November 9, 2026 (Application, 5:00 p.m. applicant organization’s local time)
Funding Amounts: $6.3 million estimated total program funding; annual direct-cost budget limit of $6.3 million for up to 5 years
Summary: Supports continued follow-up of the EDIC cohort to understand the development, progression, and prevention of type 1 diabetes complications.
Key Information: Only the current recipient under RFA-DK-21-503 may apply for this single-source renewal.
Description
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) supports continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Research Center through a collaborative U01 cooperative agreement. The program funds hypothesis-based research, cohort infrastructure and maintenance, continued follow-up, and collaborative use of EDIC data and biological and genetic samples.
The study follows about 1,000 active participants with longstanding type 1 diabetes, providing an opportunity to examine aging and diabetes-related complications. Research priorities include memory, physical ability and frailty; obesity, liver disease and obstructive sleep apnea; prediction using continuous glucose monitoring, cardiac imaging and artificial intelligence; multiomics; and the quality-of-life and economic effects of newer treatments and devices. The Research Center coordinates clinical sites, contracts, study procedures, and submission of samples and data to central facilities.
