This grant funds the continued POWERS study to complete clinical trials and analyze why people regain weight differently after losing it.
This grant has transitioned from forecasted to posted and is now accepting applications.
Funder: National Institutes of Health
Due Dates: November 17, 2026 (Application deadline)
Funding Amounts: 1 expected cooperative agreement award; no cost sharing or matching required
Summary: Supports completion of the ongoing POWERS clinical trial and analysis of data and biospecimens to understand variability in weight regain after lifestyle-induced weight loss.
Key Information: This single-source opportunity invites an application from the POWERS consortium’s Data Coordinating Center at the University of Pittsburgh.
The National Institutes of Health, through NIDDK, is supporting continuation of the Physiology of the Weight Reduced State (POWERS) clinical trial. POWERS investigates the physiological processes underlying individual differences in weight regain following weight loss achieved through a lifestyle intervention. Continuation funding will allow the ongoing trial to be completed and collected data and biospecimens to be analyzed.
This U01 cooperative agreement opportunity requires clinical trials and invites a single-source application from the POWERS consortium’s Data Coordinating Center. The application will undergo NIH’s standard peer-review process, and only meritorious applications will be considered for funding.