Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
The NIH will soon offer grants to support early-career scientists at US small businesses, funding both research and entrepreneurial training, with required mentoring for first-time principal investigators.
Funder: National Institutes of Health
Due Dates (Anticipated): January 2027 (Full application deadline, projected)
Funding Amounts: Not specified; award size and total funding to be detailed in the forthcoming NOFO.
Summary: Supports early-career scientists transitioning to entrepreneurship through research funding and entrepreneurial training for U.S. small businesses.
Key Information: Forecasted opportunity; details subject to change—monitor program page for updates.
Description
This forecasted opportunity from the National Institutes of Health (NIH) will invite eligible United States small business concerns (SBCs) to submit applications for the Small Business Transition Grant (Parent R41/R42 Clinical Trial Optional). The program is designed to support early-career scientists who are transitioning into entrepreneurship, particularly those who have not previously served as independent Principal Investigators (PD/PI) on NIH, CDC, or equivalent research grants. In addition to research and development funding, the grant emphasizes entrepreneurial training, mentoring, and career development for the PD/PI. Participation of a mentor with measurable effort committed to the project is required. The opportunity will utilize the R41/R42 activity codes, covering a broad range of NIH research areas.
