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    Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

    This upcoming NIH and CDC grant supports early-career scientists at US small businesses with funding, entrepreneurial training, and mentoring to help them transition into entrepreneurship.

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    Funder: National Institutes of Health

    Due Dates (Anticipated): January 2027 (Full application deadline, projected)

    Funding Amounts: SBIR Phase I and Fast-Track awards; specific ceiling/floor not yet announced; typical NIH SBIR Phase I awards are up to $295,924 for 6-12 months.

    Summary: Supports early-career scientists transitioning into entrepreneurship through small business-led research and structured entrepreneurial training and mentoring.

    Key Information: Forecasted opportunity; only first-time PD/PIs and U.S. small businesses eligible.


    Description

    This forecasted opportunity from the National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC) is intended to support United States small business concerns (SBCs) applying for Small Business Innovation Research (SBIR) Phase I and Fast-Track grants. The program is designed for early-career scientists transitioning into entrepreneurship, providing funding for research and development as well as structured entrepreneurial training, mentoring, and career development for the Principal Investigator (PD/PI). A key requirement is that key personnel must include a mentor with measurable effort committed to the project. This opportunity is specifically for first-time PD/PIs who have never previously served as an independent PD/PI on an NIH, CDC, or corresponding non-NIH peer-reviewed research grant.


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