[U.S. National Science Foundation](https://www.nsf.gov/)

October 3, 2025

Up to $1,200,000 per award; approximately $20 million total program funding; ~16 awards expected

Supports high-risk, high-reward interdisciplinary research advancing AI, data science, and related fields to address major biomedical and public health challenges.

--- ## Description This opportunity supports transformative interdisciplinary research at the intersection of artificial intelligence, advanced data science, and biomedical/public health domains. The aim is to foster high-risk, high-reward projects that develop innovative methods for collecting, analyzing, and interpreting complex health-related data. The solicitation encourages the formation of teams that bridge computer science, engineering, mathematics, statistics, behavioral, and cognitive sciences to tackle significant biomedical or public health problems, while advancing fundamental science and engineering. --- ## Due Dates - Full proposals due: October 3, 2025 --- ## Funding Amount - Maximum award: $1,200,000 per project - Estimated total program funding: $20,000,000 - Expected number of awards: Approximately 16 - No cost sharing or matching required --- ## Eligibility Applicants must be one of the following: - **Non-profit, non-academic organizations**: Includes independent museums, observatories, research laboratories, professional societies, and similar U.S.-based organizations directly associated with educational or research activities. - **Institutions of Higher Education (IHEs)**: Accredited U.S. two- and four-year IHEs (including community colleges), acting on behalf of their faculty members. **Special note for international branch campuses of U.S. IHEs:** Proposals involving funding to international branch campuses must justify why project activities cannot be performed at the U.S. campus and explain the benefits of conducting work at the international branch. --- ## Application Process - Applications must be submitted electronically via [Grants.gov](https://www.grants.gov/search-results-detail/360142). - Review the [NSF Publication 25-542](http://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf25542) for detailed solicitation requirements. - Prepare proposals according to NSF’s [Proposal & Award Policies & Procedures Guide (PAPPG)](https://www.nsf.gov/policies/pappg/24-1). - Ensure all required documents and eligibility criteria are met before submission. --- ## Additional Information - This is an interagency program; multiple NSF directorates and NIH institutes participate. - Projects should emphasize transformative, interdisciplinary approaches and may address a wide range of biomedical and public health topics. - No cost sharing or matching is required. - Award duration and specific project period will be defined in the award notice. --- ## External Links - [NSF Program Page](https://www.nsf.gov/funding/opportunities/sch-smart-health-biomedical-research-era-artificial-intelligence) - [Grants.gov Opportunity Listing](https://www.grants.gov/search-results-detail/360142) - [NSF Publication 25-542](http://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf25542) - [NSF Proposal & Award Policies & Procedures Guide](https://www.nsf.gov/policies/pappg/24-1) --- ## Contact Information | Contact | Email | Description | |-----------------------------------|-----------------------------------------|-------------------------------------------| | NSF Grants.gov Support | grantsgovsupport@nsf.gov | For technical issues or access problems | For programmatic questions, refer to the [NSF program page](https://www.nsf.gov/funding/opportunities/sch-smart-health-biomedical-research-era-artificial-intelligence) for updated contact details.

Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science

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