AHA has updated the description for this opportunity to explicitly encourage multidisciplinary approaches like AI in imaging, biomarker discovery, risk prediction, and non-surgical management. You will also find newly added timeline details, including a March 2026 notification date and an April 1, 2026 award start date, plus a direct link to the full RFP.
Funder: American Heart Association
Due Dates: October 29, 2025: Required pre-proposal (by 4:00 p.m. ET / 3:00 p.m. CT) | January 21, 2026: Full proposal (invitation-only) (by 4:00 p.m. ET / 3:00 p.m. CT)
Funding Amounts: Up to $4,400,000 per Center over 4 years; includes direct and indirect costs, with a separate network-wide collaborative project budget (up to $1.8M for the network).
Summary: Supports collaborative, multidisciplinary research centers advancing early detection and delaying progression of valvular heart disease.
Key Information: AHA Professional Membership is required for Center Directors and Project PIs at submission.