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    Strategies to Innovate Emergency Care Clinical Trials Network Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)

    Forecasted

    NIH seeks applications for centers to coordinate and support clinical trials aimed at improving emergency care for neurological and cardiovascular conditions through the SIREN network.

    Funder: National Institutes of Health

    Due Dates (Anticipated): March 2027 (Full application deadline, projected)

    Funding Amounts: Expected 2 awards; funding amount not specified; cooperative agreement for multi-year clinical trial network infrastructure

    Summary: Supports infrastructure for the SIREN Network to conduct clinical trials on non-stroke neurological and cardiovascular emergencies in pre-hospital and emergency department settings.

    Key Information: Forecasted opportunity; applications not yet being solicited; advance notice for collaboration building.


    Description

    The National Institutes of Health (NIH), through the National Institute of Neurological Disorders and Stroke (NINDS) and the National Heart, Lung, and Blood Institute (NHLBI), anticipates a funding opportunity to support the infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). This program funds a Clinical Coordinating Center (CCC) and a Data Coordinating Center (DCC) to enable multi-site clinical trials focused on improving outcomes for individuals experiencing non-stroke neurological and cardiovascular emergencies, particularly in pre-hospital and emergency department settings. The goal is to identify and test effective early interventions through robust, collaborative clinical research. This notice is a forecast to allow potential applicants time to develop partnerships and prepare responsive applications; applications are not currently being accepted.


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