[National Institutes of Health](https://www.nih.gov)

April 2027 | April 2026

Award size and total funding not yet specified; cooperative agreement mechanism; details expected at solicitation release.

Supports multidisciplinary research consortia focused on structure-based immunogen design for HIV prevention and control, advancing broadly neutralizing antibody approaches toward clinical testing.

--- ## Description This forecasted opportunity from the National Institutes of Health (NIH) aims to support coordinated, multidisciplinary research consortia focused on structure-based immunogen design to prevent and control HIV. The program seeks to develop HIV immunogens and treatment strategies leveraging or inducing broadly neutralizing antibodies (bNAbs), with the goal of advancing these approaches toward clinical testing for both prevention and therapy. Technologies and methods developed through this initiative are expected to have broad applicability to other fields facing similar challenges in antigen targeting for therapeutics and vaccine development. --- ## Due Dates - April 2027 (anticipated full application deadline) - April 2026 (anticipated application deadline; past cycle) *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Award size and total program funding are not yet specified for this forecasted opportunity. - Funding will be provided as a cooperative agreement (UM1). - Details on the number of awards, award ceiling, and duration will be available in the full solicitation upon release. --- ## Eligibility Eligible applicants include: - Public and private institutions of higher education - State, county, city, or township governments - Special district governments - Independent school districts - Federally recognized and other Native American tribal governments and organizations - Public housing authorities/Indian housing authorities - Nonprofits with or without 501(c)(3) status (excluding those that are institutions of higher education) - For-profit organizations (including small businesses) - Eligible agencies of the federal government - U.S. territories and possessions - Faith-based and community-based organizations - Regional organizations --- ## Application Process - This is a forecasted opportunity; the full Notice of Funding Opportunity (NOFO) and application instructions will be published closer to the anticipated due date. - Applications will likely be submitted via [Grants.gov](https://www.grants.gov/search-results-detail/360591). - Monitor the program page for updates regarding the release of the full solicitation and required application components. --- ## Additional Information - No cost sharing or matching is required. - Clinical trials are not allowed under this funding opportunity. - The initiative is expected to foster collaboration among multidisciplinary teams to accelerate immunogen discovery and translational research. --- ## External Links - [NIH Main Website](https://www.nih.gov) - [Grants.gov Opportunity Listing](https://www.grants.gov/search-results-detail/360591) --- ## Contact Information | Name | Email | Phone | |---------------------------|-----------------------------------|---------------| | Stuart Z. Shapiro, M.D., Ph.D. | [sshapiro@niaid.nih.gov](mailto:sshapiro@niaid.nih.gov) | 240-292-6155 |

Consortia for Structure-based Immunogen Design for HIV (CSID-HIV)

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