Translational Transplantation Tolerance Cooperative Study Group
This grant supports a multi-center program to develop and test new methods for achieving long-term transplant tolerance without lifelong immunosuppressive drugs.
Funder: National Institutes of Health
Due Dates (Anticipated): May 2027 (Full application deadline, projected)
Funding Amounts: $10,460,000 total program funding (projected); award ceiling not specified; duration typically aligns with NIH multi-year cooperative agreements.
Summary: Supports a multi-center collaborative program to develop and evaluate transplant immune tolerance regimens that enable long-term graft survival without lifelong immunosuppression.
Key Information: This is a forecasted opportunity; all deadlines and details are subject to change.
Description
The National Institute of Allergy and Infectious Diseases (NIAID) anticipates supporting the Translational Transplantation Tolerance Cooperative Study Group (TTTCSG). This program aims to advance clinical translation of safe and effective transplant tolerance regimens, with the goal of achieving durable graft survival without the need for lifelong immunosuppressive drugs. The initiative will establish a collaborative, multi-center research group dedicated to developing, optimizing, and testing approaches to induce and maintain immune tolerance to allogeneic transplants. Projects are expected to use translationally relevant models and foster cooperation across institutions.
