Large-Scale Science Transition Funding Program (LSSTF)
Large-Scale Science Transition Funding Program (LSSTF) supports Alzheimer's and related dementias research teams, funding continuity of science and operations as they move toward more stable funding.
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Funder: Alzheimer's Association
Due Dates: December 15, 2026 (Pre-submission query) | Six weeks after invitation (Full application)
Funding Amounts: $200,000–$1,000,000 for up to 12 months; no indirect costs
Summary: Supports established Alzheimer's and related dementias research initiatives through funding transitions while sustaining their science, teams, and study operations.
Key Information: Applicants must be PIs or multiple PIs on a qualifying NIH cooperative award or equivalent; support is limited to once per underlying award.
Description
The Alzheimer's Association's Large-Scale Science Transition Funding Program (LSSTF) supports major Alzheimer's disease and related dementias research initiatives built on NIH cooperative awards. It funds the transition to a new stage of development, different funding mechanisms, or an adjusted program scale—not new scientific projects, scope expansion, or bridge support without a defined endpoint.
Support focuses on retaining essential investigators and study personnel, sustaining data collection and biospecimen operations, and planning diversified funding through co-funding partnerships, industry collaboration, or philanthropy. Applicants must demonstrate a credible one-year path toward a more stable or diversified funding structure. The program aims to preserve established cohorts, datasets, biospecimens, infrastructure, and collaborative teams while that transition takes place.
