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    Large-Scale Science Transition Funding Program (LSSTF)

    Large-Scale Science Transition Funding Program (LSSTF) supports established Alzheimer's and related dementias research teams, funding personnel, study operations, and planning to sustain research through funding transitions.

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    Funder: Alzheimer's Association

    Due Dates: December 15, 2026, 5 p.m. ET (Pre-submission query) | Six weeks after invitation, 5 p.m. ET (Full application)

    Funding Amounts: $200,000–$1,000,000 for up to 12 months; no indirect costs

    Summary: Supports established Alzheimer's and related dementias research initiatives through funding transitions, sustaining essential personnel, study operations, and funding diversification planning.

    Key Information: Applicants must be associated with a qualifying NIH U01, U19, U24, U54, or equivalent award; funding is available only once per underlying award.


    Description

    The Alzheimer's Association's Large-Scale Science Transition Funding Program (LSSTF) supports major Alzheimer's disease and related dementias research initiatives built on NIH cooperative awards. It helps established initiatives move to their next development stage, pursue new funding mechanisms, or adjust their scale while preserving scientific assets and collaborative teams.

    Funding supports scientific continuity through retention of essential investigators and personnel, study continuity through ongoing data collection and biospecimen operations, and diversification planning through co-funding, industry, or philanthropic partnerships. Applicants must present a credible one-year path toward a more diversified or stable funding structure. The program funds the transition itself—not new scientific projects, expansion of an initiative's scope, or open-ended bridge support without an endpoint and plan.


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