Artificial intelligence in cell culture media and process development
Forecasted
Artificial intelligence in cell culture media and process development supports researchers building adaptable models to optimize media feeds across mammalian hosts, improving bioprocess efficiency and conserving resources.
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Funder: Merck KGaA (EMD Group)
Due Dates (Anticipated): August 2027 (Application deadline)
Funding Amounts: Up to one grant of €150,000 per year for up to three years
Summary: Supports adaptable models that predict optimized cell culture media feeds for bioprocessing.
Key Information: Initial proposals must use non-confidential information only.
Description
Merck KGaA, Darmstadt, Germany, offers this research grant for models that predict optimized media feeds for bioprocessing. It seeks robust, host-agnostic models that are easy to parameterize and can support fit-for-purpose process optimization across a broad range of host organisms. Mechanistic or hybrid modeling may help clarify the nutrient requirements of mammalian cell lines, while artificial intelligence may help analyze complex systems such as CHO and HEK293 cells.
Proposals should identify the model and key parameters relevant to optimizing cell culture media and set out a data strategy for continuous improvement across mammalian hosts. The goal is to improve process efficiency while conserving resources, supporting sustainability and affordability, maintaining product quality, and broadening patient access.
