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    Accelerating Safe Clinical Evaluation of Novel Treatments: Ibogaine for Better Outcomes in Opioid Use Disorder (ASCENT-IBO)

    ASCENT-IBO supports multidisciplinary teams conducting Phase 1 and 2 ibogaine trials to establish safety and effectiveness for high-risk opioid use disorder and prepare for Phase 3 testing.

    OverviewSimilar Grants
    OverviewSimilar Grants

    This grant was recently updated

    ASCENT-IBO now accepts submissions only from applicants who met previous deadline requirements; encouraged proposals are due by the assigned deadlines in Solution Summary feedback letters. New FAQs clarify eligibility, scope and budget requirements, and other application details also changed.

    Cooperative Agreement to Support Activities Related to Analgesics, Anesthetics, and Addiction (U01) Clinical Trials Allowed

    This grant supports clinical trials and research to improve pain management, addiction treatment, anesthesia safety, and drug prescribing practices.

    HHS-FDA$2,000,000Forecasted

    Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)

    Use existing data to analyze drug use behaviors, prevention strategies, and service utilization, aiming to advance substance use research.

    HHS-NIH11Due Nov 3, 2026· 5d

    Opioid Abatement (2026)

    Opioid Abatement (2026) supports North Carolina higher education researchers studying opioid prevention and remediation to develop practical, evidence-based guidance for state and local policy and practice.

    NC CollaboratoryDue Oct 31, 2026· 2d$300,000

    Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

    This grant supports research using advanced single cell techniques to study how substance use disorders and HIV interact in the brain, aiming to uncover mechanisms and identify new therapy targets.

    HHS-NIH11Forecasted Jun 8, 2027$1,000,000Forecasted

    Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional)

    Supports high-risk, high-impact research on HIV and substance use to advance HIV prevention, diagnosis, treatment, and virus suppression among people who use substances or have substance use disorders.

    HHS-NIH11Due Sep 25, 2027$3,500,000