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    BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01 Basic Experimental Studies with Humans Required)

    Forecasted

    This grant will fund collaborative research using invasive neural recording and stimulation in humans to investigate fundamental questions about brain function and behavior.

    Funder: National Institutes of Health

    Due Dates: February 27, 2026 (anticipated)

    Funding Amounts: Funding details not yet specified; cooperative agreement (U01); award ceiling/floor not listed.

    Summary: Supports fundamental research using invasive neural recording and stimulation in humans to advance understanding of human brain function.

    Key Information: This is a forecasted opportunity; application details and funding amounts will be finalized in the official NOFO.


    Description

    The National Institute of Neurological Disorders and Stroke (NINDS), in collaboration with several NIH Institutes and Centers, intends to support research that leverages invasive neural recording and stimulating technologies in the human brain. This initiative aims to enable experimental investigations into fundamental aspects of human neuroscience—such as perception, memory, decision-making, language, emotion, and movement—by utilizing direct intracranial access during surgical procedures. The program encourages innovative, collaborative projects that combine expertise from clinical, scientific, engineering, data science, regulatory, and ethical domains. The overarching goal is to generate new insights into human brain function that are otherwise unattainable, with potential relevance to understanding and treating nervous system disorders.


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