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    Clinical Pilot - Alpha-1 Foundation

    Clinical Pilot supports researchers, including promising new investigators, in human-subject studies testing new hypotheses or methods for AAT deficiency, toward better health and ultimately a cure.

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    Funder: Alpha-1 Foundation

    Due Dates: September 25, 2026 (Letter of Intent) | February 12, 2027 (Invited full application)

    Funding Amounts: Up to $75,000 for one year (maximum total award: $75,000)

    Summary: Supports human-subject research testing new hypotheses or methods relevant to alpha-1 antitrypsin deficiency.

    Key Information: Pharmaceutical companies, biotechs, and industry may not apply or collaborate on proposals.


    Description

    The Clinical Pilot grant is part of the Alpha-1 Foundation’s 2026–2027 In-Cycle Grants Award Program. It supports research involving human subjects that develops and tests new hypotheses or new methods relevant to alpha-1 antitrypsin (AAT) deficiency. Methods being applied to Alpha-1 problems for the first time are also within scope.

    The program also supports promising new investigators as they establish themselves in research areas relevant to Alpha-1. Its emphasis is on exploring new ideas and approaches through human-subject research, contributing to the Foundation’s broader goals of improving the health of individuals with AAT deficiency and ultimately finding a cure.


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