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    Clinical Pilot and Feasibility Award

    Clinical Pilot and Feasibility Award supports investigators testing new cystic fibrosis hypotheses or methods in human subjects or samples to generate preliminary data for larger studies.

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    Funder: Cystic Fibrosis Foundation

    Due Dates: October 1, 2026 (Spring 2027 LOI) | February 17, 2027 (Spring full application) | March 31, 2027 (Fall 2027 LOI) | August 18, 2027 (Fall full application)

    Funding Amounts: Up to $80,000/year (single-center) or $150,000/year (multicenter), plus 12% indirect costs, for up to two years

    Summary: Supports human-subject or sample-based cystic fibrosis research testing new hypotheses or methods and generating preliminary data for larger studies.

    Key Information: Full applications are invitation-only following an approved LOI, unless an LOI bypass is approved.


    Description

    The Cystic Fibrosis Foundation’s Clinical Pilot and Feasibility Award supports projects involving human subjects or samples that develop and test new hypotheses or methods relevant to cystic fibrosis (CF), including methods applied to CF for the first time. The goal is to generate preliminary data that identify effective strategies for a major question requiring larger-scale research or a multicenter collaborative trial. The program also supports promising investigators establishing themselves in CF research.

    Projects may address diagnosis, treatment, disease or symptom management, or CF pathophysiology through observational, interventional, translational, or epidemiologic approaches. Special consideration goes to new approaches, under-researched topics, and creative research avenues. Preliminary data are not required, but applicants must provide sufficient background and rationale for human-subject research.


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