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    Clinical Trials to Validate AI-Driven Drug Repurposing 2026

    Forecasted

    Cures Within Reach funds clinical trials using AI to validate repurposed therapies for unsolved diseases, prioritizing rare conditions and explainable AI workflows.

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    AI in Healthcare Research GrantsAI Research Grants 2026
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    Repurposing Research for Chicago 2026: Track 2 – Patient Groups

    Repurposing Research for Chicago 2026: Track 2 – Patient Groups supports Chicago-area researchers testing repurposed therapies to address unsolved diseases in underserved and priority patient groups.

    Cures Within ReachForecasted May 8, 2027$125,000Forecasted

    Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)

    Use mouse models to test existing and investigational drugs for Alzheimer's; focus on drug repositioning and combo therapy development.

    HHS-NIH11Due Feb 8, 2027$5,000,000

    Repurposing Generic (ReGen) Drugs Evidence Package Challenge

    Repurposing Generic (ReGen) Drugs Evidence Package Challenge supports individuals, teams, and entities reviewing evidence for new generic drug uses to expand affordable treatment for high-cost conditions.

    NIH ChallengesDue Jan 15, 2027$100,000

    2025: ALS Finding a Cure Request for Proposals

    ALS Finding a Cure funds research using AI and NLP to advance ALS diagnostics, biomarker discovery, disease modeling, and therapeutic innovation.

    ALSFACForecasted May 23, 2027$400,000Forecasted

    Utilizing Real-World Data and Algorithmic Analyses to Assess Post-Market Clinical Outcomes in Patients Switching Amongst Therapeutically Equivalent Complex Generic Drug Products and Reference Listed Drugs (U01) Clinical Trial Not Allowed

    This grant seeks to develop AI/ML models using real-world data to monitor clinical outcomes when patients switch between complex generics and brand-name drugs.

    HHS-FDA$300,000Forecasted