[Cancer Research Institute](https://www.cancerresearch.org)

November 15, 2025 (Letter of Intent) | March 2, 2026 (Invited Full Application)

Up to $600,000 over 2–4 years; 10% indirect costs allowed, in addition to the award.

Supports early-stage, high-risk technology innovations with transformative potential for cancer immunotherapy through collaborative research.

--- ## Description The program provides seed funding for bold, early-stage, pre-development technology concepts that could revolutionize cancer immunotherapy. It aims to bridge the gap between innovative ideas and clinical application, encouraging close collaboration between technology developers and clinical cancer immunologists. The focus is on high-risk, high-reward proposals capable of overcoming major barriers in the field and enabling the next generation of personalized, durable cancer immunotherapies. Supported areas include computational systems biology, advanced profiling, real-time visualization, complex multicellular culture systems, and novel therapeutic platforms. The program does not support incremental improvements to existing technologies or clinical trials, but technologies that leverage samples from independent trials are eligible. --- ## Due Dates - November 15, 2025: Letter of Intent deadline - March 2, 2026: Invited full application deadline Applicants are notified by mid-February if invited to submit a full proposal. If a deadline falls on a weekend, submissions are accepted the following Monday. Applications are due by 11:59 p.m. Eastern Time. --- ## Funding Amount - Up to $600,000 total over 2–4 years - 10% indirect costs allowed, provided in addition to the award - Awards activate on the first of the month, with the earliest start date of July 1 following the application cycle Funds are intended for technology development and may not be used for clinical trial costs. --- ## Eligibility - Applicants must hold a tenure-track position at a non-profit research center or institution (U.S. or international). - No citizenship restrictions. - Collaborative proposals (e.g., between clinical immunologists and technology developers) are encouraged; co-PIs are allowed. - Proposals must be non-overlapping with other CRI programs. - Multiple applicants from the same institution may apply if projects are scientifically distinct. --- ## Application Process 1. **Letter of Intent (LOI):** Submit electronically via the [CRI Grants Portal](https://cri.us-1.smartsimple.com/s_Login.jsp) by the LOI deadline. 2. **Full Application:** By invitation only, following LOI review. 3. **Submission Materials:** - Research concept (≤3 pages) with aims, timeline, and transformative potential - Brief description of current research - Curriculum vitae (NIH biosketch accepted) - Bibliography (last 5 years or relevant publications) - CVs for all group members and roles, if applicable 4. **Formatting:** PDF format, single-spaced, minimum 12pt font; adhere to page limits. 5. **Notification:** LOI decisions by mid-February; full application decisions within 12–16 weeks of deadline. --- ## Additional Information - Indirect costs (up to 10%) are provided in addition to the award. - Intellectual property developed must be disclosed annually using CRI forms. - Revenue sharing applies to inventions/commercialization per CRI policy; the first $250,000 of net income is exempt. - Applications exceeding page limits or submitted in incorrect formats will be disqualified. - Incomplete or late applications will not be considered. --- ## External Links - [Full Program Details & Application](https://www.cancerresearch.org/technology-impact-award) - [CRI Grants Portal (Apply)](https://cri.us-1.smartsimple.com/s_Login.jsp) - [Program FAQs](https://www.cancerresearch.org/programs-faqs) - [Invention Disclosure Form (PDF)](https://www.cancerresearch.org/wp-content/uploads/2025/08/CRI-Invention-Disclosure-Form-1-2025.pdf) - [Annual Invention Update Form (PDF)](https://www.cancerresearch.org/wp-content/uploads/2025/08/Annual-Invention-Update-Form-1-2025.pdf) - [Revenue Sharing Agreement (PDF)](https://www.cancerresearch.org/wp-content/uploads/2022/10/Revenue-Sharing-Agreement.pdf) - [List of Past Awardees](https://www.cancerresearch.org/cri-funded-scientists?grant=tech-impact-award) --- ## Contact Information | Contact | Details | |------------------------|-------------------------------------------------------------| | General Inquiries | [grants@cancerresearch.org](mailto:grants@cancerresearch.org) | | Phone | (800) 992-2623 | | Address | Cancer Research Institute, 29 Broadway, Floor 4, New York, NY 10006-3111 | | Online Contact Form | [Contact CRI](https://www.cancerresearch.org/contact) |

CRI Technology Impact Award - Cancer Research Institute

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