Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)
Forecasted
This grant funds innovative research to develop or improve broadly applicable models, materials, and methodologies for studying multiple body systems or diseases relevant to human health, excluding single disease or system studies.
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Funder: National Institutes of Health
Due Dates (Anticipated): February 2028
Funding Amounts: Up to $500,000 per award; minimum $190,000; approx. 15 awards expected.
Summary: Supports the development, improvement, and characterization of research models, biological materials, and new methodologies broadly relevant to human health and diseases.
Key Information: Applications focused on a single disease, body system, or NIH Institute are not eligible.
Description
This opportunity supports innovative research to develop, characterize, improve, or preserve research models and related biological materials, as well as to develop or enhance new approach methodologies (NAMs) and technologies for studying human health and diseases. The program particularly encourages projects aimed at improving the identification and control of factors that may confound or interfere with the use of research models in biomedical research.
Projects must:
- Have broad applicability across multiple NIH Institutes or Centers (ICs) in alignment with the NIH-wide mission of the Office of Research Infrastructure Programs (ORIP).
- Include research models or NAMs that explore multiple body systems or multiple categories of diseases affecting multiple systems.
Applications focused on a single disease, a narrow research area, a single body system, or primarily relevant to one NIH IC will not be considered.
