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    Utilizing Real-World Data and Algorithmic Analyses to Assess Post-Market Clinical Outcomes in Patients Switching Amongst Therapeutically Equivalent Complex Generic Drug Products and Reference Listed Drugs (U01) Clinical Trial Not Allowed

    Forecasted

    This grant seeks to develop AI/ML models using real-world data to monitor clinical outcomes when patients switch between complex generics and brand-name drugs.

    OverviewSimilar Grants
    OverviewSimilar Grants

    Integrating Machine Learning with Computational Fluid Dynamics Models of Orally Inhaled Drug Products (U01) Clinical Trials Not Allowed

    This grant aims to combine machine learning and computational fluid dynamics to improve generic inhaled drug development and approval through alternative bioequivalence studies.

    HHS-FDAForecasted

    Clinical Trials to Validate AI-Driven Drug Repurposing 2026

    Cures Within Reach funds clinical trials using AI to validate repurposed therapies for unsolved diseases, prioritizing rare conditions and explainable AI workflows.

    Cures Within ReachForecasted Jun 26, 2027$100,000Forecasted

    Improving Predictability of Food-Drug and Drug-Drug Interaction Risks by Utilizing In Vitro Simulated Gastrointestinal Dissolution Model for High-Risk Oral Drug Products (U01) Clinical Trial Optional

    This grant aims to improve prediction of food/drug interactions for high-risk oral drugs by using a lab model that mimics the gut to assess drug performance.

    HHS-FDA$500,000Forecasted

    Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)

    This grant funds innovative natural history studies to advance medical product development and address unmet needs in rare diseases by generating high-quality, interpretable data.

    HHS-FDADue Jan 7, 2028$2,400,000

    Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)

    This grant funds innovative natural history studies to improve understanding and support medical product development for rare diseases with unmet needs.

    HHS-FDA$400,000Forecasted