[Breakthrough T1D](https://www.breakthrought1d.org)

October 2026 (Full proposal deadline, projected)

Up to $200,000 (including up to 10% indirect costs) for 1 year; not renewable; higher budgets or longer durations may be considered with strong justification.

Supports high-risk, high-reward, and conceptually novel research projects with transformative potential for type 1 diabetes.

--- ## Description The Innovative Awards from Breakthrough T1D are designed to catalyze bold, transformative research in type 1 diabetes (T1D) by supporting high-risk, high-reward, or conceptually novel projects that may not yet be funded by traditional mechanisms. The program seeks to drive significant breakthroughs in understanding, preventing, treating, or curing T1D by enabling new ideas and approaches that challenge current paradigms or lead to groundbreaking discoveries. Preliminary data are not required, but proposals must present a plausible and testable hypothesis with a well-defined, achievable goal within the one-year funding period. --- ## Due Dates - October 2026 (anticipated/projected, full proposal deadline) *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Maximum award: $200,000 (including up to 10% for indirect costs) for a one-year project. - Awards are not renewable. - Larger budgets or multi-year projects may be considered at the discretion of Breakthrough T1D with strong justification; applicants should contact program staff to discuss exceptions. --- ## Eligibility - Applicants must hold an M.D., D.M.D., D.V.M., D.O., Ph.D., or equivalent degree and a faculty position (or equivalent) at a college, university, medical school, or other research facility. - Eligible institutions include domestic and foreign non-profit organizations, public and private universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government. - For-profit organizations may submit innovative (but not pilot or research tool) proposals. - All projects must be relevant to type 1 diabetes and aligned with Breakthrough T1D’s mission and research strategy. - There are no citizenship requirements. --- ## Application Process 1. **Review Materials:** Download and review the [Grant Handbook](https://www.breakthrought1d.org/granthandbook/) and the [Innovative Awards RFA](https://www.breakthrought1d.org/wp-content/uploads/2025/10/FY26-Innovative-RFA_Revised.pdf) for detailed instructions, eligibility, and requirements. 2. **Prepare Application:** No Letter of Intent (LOI) is required for Innovative Awards. Prepare a full proposal using the template provided through the RMS360 portal. The research plan must not exceed 3 pages (excluding references). 3. **Submission:** Submit the full application via [RMS360](https://breakthrought1d.smartsimple.us/) by the anticipated deadline. 4. **Attachments:** Required attachments include biosketches for PI and key personnel, research plan, abstracts (scientific and lay), budget, and any required assurances for human subjects or animal research. 5. **Review:** Proposals are reviewed by Breakthrough T1D staff scientists for innovation, impact, feasibility, clarity, and alignment with organizational priorities. 6. **Notification:** Applicants are notified of funding decisions following review and governance approval. --- ## Additional Information - Indirect costs are capped at 10% of direct costs (excluding equipment, fee-for-services, consultants, or subcontract costs). - The program does not support incremental advances or projects focused solely on generating reagents/resources. - If a project requires a larger budget or longer duration, contact Breakthrough T1D program staff before applying. - Human subjects research must comply with relevant guidelines; see the [Grant Handbook](https://www.breakthrought1d.org/wp-content/uploads/2024/07/granthandbook.pdf) for details. - Resubmissions must include a summary statement and a rebuttal letter addressing reviewer comments. --- ## External Links - [Breakthrough T1D Central Funding Opportunities](https://www.breakthrought1d.org/explore-research/funding-opportunities/) - [Grant Handbook](https://www.breakthrought1d.org/granthandbook/) - [FY26 Innovative Awards RFA (PDF)](https://www.breakthrought1d.org/wp-content/uploads/2025/10/FY26-Innovative-RFA_Revised.pdf) - [RMS360 Application Portal](https://breakthrought1d.smartsimple.us/) --- ## Contact Information | Purpose | Contact | |-----------------------------|--------------------------------------------------------------------------------------------------| | General/Preaward Support | [preawardsupport@breakthrought1d.org](mailto:preawardsupport@breakthrought1d.org) | | Scientific/Program Queries | Refer to contact instructions in the [Innovative Awards RFA](https://www.breakthrought1d.org/wp-content/uploads/2025/10/FY26-Innovative-RFA_Revised.pdf) | | Web Contact Form | [Breakthrough T1D Contact Us](https://www.breakthrought1d.org/contact-us/) |

FY26 Innovative Awards

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