Genomic Data Generation Center for the Gabriella Miller Kids First Pediatric Research Program (U24 Clinical Trial Not Allowed)
Supports centers generating high-quality genomic data from human specimens representing childhood cancers and congenital anomalies for the Gabriella Miller Kids First Pediatric Research Program.
This grant was recently updated
This grant has transitioned from forecasted to posted and is now accepting applications.
Funder: National Institutes of Health
Due Dates: January 8, 2027 (Application, 5:00 p.m. local time) | December 8, 2026 (Earliest submission)
Funding Amounts: Up to $3.5 million per year in direct costs for up to 3 years; $6 million estimated program funding
Summary: Supports centers generating genomic, transcriptomic, and epigenomic data from pediatric cancer and congenital anomalies cohorts for the Kids First Data Resource.
Key Information: Clinical trials are not allowed; centers must deliver data to the Kids First Data Resource Center.
Description
The NIH Gabriella Miller Kids First Pediatric Research Program supports Genomic Data Generation Centers that rapidly produce high-quality sequence and variant data from large numbers of human specimens. Supported work includes whole-genome and long-read DNA sequencing, RNA sequencing, genome-wide methylation profiling, and chromatin accessibility assays for childhood cancer and congenital anomalies cohorts selected by the Kids First Program.
Centers will coordinate with cohort investigators and the Kids First Data Resource Center (DRC), which reprocesses and harmonizes data for sharing through a cloud-based resource. The program seeks insights into disease biology and shared genetic pathways that could inform prevention, diagnostics, and targeted interventions. Centers are expected to maximize sample throughput while maintaining or improving quality and reducing costs over the award period.
