NCI funds collaborative teams to develop therapies for adult glioblastoma that cross the blood-brain barrier, advancing novel or repurposed agents from preclinical studies into Phase 0/1 trials.
Funds research on gene-edited NK cells and oncolytic viruses to enhance immunotherapy for glioblastoma by overcoming tumor-induced immune suppression.
Funding opportunity for advancing nanotechnology-based cancer treatments to improve effectiveness through innovative nanoparticle designs and cargos.
Funding support available to study and prove effectiveness of potential neurotherapeutic agents for neurological disorders towards further development.
NIH supports development of next-generation diagnostic and therapeutic devices aligned with its brain research and addiction initiatives, preparing them for first-in-human trials; clinical trials are not allowed.
This grant supports studies & planning for early clinical trials of gene-based therapies for ultra-rare neurological & neuromuscular disorders.