The Department of State seeks proposals to support the America First Global Health Strategy by strengthening health systems, saving lives, and advancing U.S. and global health security priorities.
Funder: Bureau of Global Health Security and Diplomacy
Due Dates: December 3, 2026 (Window 4 questions) | January 29, 2027 (Window 4 SOI) | February 14, 2027 (Final closing)
Funding Amounts: $500,000–$250 million per award for up to five years; estimated total program funding $2,147,483,647
Summary: Supports overseas projects advancing global health priorities, strengthening health systems, and fostering country self-reliance through specific funding addenda.
Key Information: Statements of Interest must respond to a specific addendum; general concepts under the umbrella APS will not be considered.
The U.S. Department of State’s Bureau of Global Health Security and Diplomacy administers this Annual Program Statement (APS) to advance the America First Global Health Strategy. It supports projects that complement, extend, or fill gaps in bilateral health Memoranda of Understanding (MOUs), including targeted technical, operational, and catalytic support for implementation and transition to country-led systems.
Funding priorities are announced through country-specific and service-specific addenda developed with U.S. embassies and other Department offices. Areas include outbreak response, child development and protection, surveillance, neglected tropical disease elimination, nutrition, and country health-system implementation. The program aims to save lives, strengthen health systems, improve efficiency, and reduce reliance on foreign assistance while advancing American safety, strength, and prosperity. Detailed knowledge of individual MOUs is not required for a competitive Statement of Interest (SOI).