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    Harnessing Digital Health Technologies To Support Patient-Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement -- Cycle 1 2027

    PCORI funds research using digital health technologies to improve patient-centered clinical care and address evidence gaps through stakeholder-engaged studies.

    Funder: Patient-Centered Outcomes Research Institute

    Due Dates: January 6, 2027 (LOI) | May 4, 2027 (Full application)

    Funding Amounts: Up to $12 million direct costs per award; project period up to 5 years; total available funds up to $60 million.

    Summary: Supports patient-centered comparative effectiveness research leveraging digital health technologies to address evidence gaps and improve healthcare outcomes.

    Key Information: LOI required for application; projects must demonstrate meaningful patient and stakeholder engagement.


    Description

    This Patient-Centered Outcomes Research Institute (PCORI) funding opportunity supports high-impact, patient-centered comparative clinical effectiveness research (CER) that leverages digital health technologies (DHTs). The initiative seeks to advance the integration and use of tools such as mobile health applications, wearables, implantable devices, artificial intelligence, and remote monitoring in healthcare. Projects should address evidence gaps related to the use of DHTs for self-management, integration of patient-generated data into clinical workflows, and individualized health management. Emphasis is placed on addressing challenges such as interoperability, digital literacy, accessibility, and equitable uptake across diverse populations. Meaningful engagement of patients and stakeholders is a core requirement throughout all project phases.


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