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    Harnessing Digital Health Technologies To Support Patient-Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement -- Cycle 1 2027

    Harnessing Digital Health Technologies supports researchers studying digital health tools through patient-centered comparisons to close evidence gaps and help patients and clinicians make informed care decisions.

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    Funder: Patient-Centered Outcomes Research Institute

    Due Dates: January 6, 2027, 5 pm ET (LOI) | May 4, 2027, 5 pm ET (Application)

    Funding Amounts: Up to $12 million in direct costs per project for up to five years; up to $60 million available

    Summary: Supports patient-centered comparative clinical effectiveness research addressing evidence gaps in digital health technologies.

    Key Information: The specific digital health technology must have evidence of efficacy or widespread use, with product development complete.


    Description

    The Patient-Centered Outcomes Research Institute (PCORI) supports high-impact comparative clinical effectiveness research on digital health technologies, including mobile health applications, wearable and implantable devices, patient-generated data tools and artificial intelligence. Studies should fill evidence gaps and produce patient-centered clinical outcomes that help patients, clinicians and other healthcare partners make informed decisions.

    The initiative emphasizes patient self-management, integration of patient-generated data into clinical workflows and individualized health management. These areas encourage, but do not limit, submissions. Priorities include accessibility, usability, sustained engagement, care coordination and identifying which patients benefit most. Remote-care tools may be responsive, but telehealth versus in-person comparisons without compelling justification are low priority. Patients and healthcare partners are expected to contribute meaningfully throughout the research.


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