NIH supports phased clinical research lasting up to five years to identify mechanisms driving joint pain and test non-pharmacologic or multimodal interventions targeting them.
Funding for research developing non-addictive pain treatments through early drug discovery to support the Pain Therapeutics Development Program.
NIH supports research centers conducting clinical trials to improve integrated care for people with both chronic pain and opioid use disorder.
NIH supports milestone-driven development of non-addictive small molecule and biologic pain treatments, from lead optimization through Phase I testing, to prepare candidates for Phase II trials.
This upcoming NIH grant will fund multidisciplinary research to better understand joint pain, improve joint health, and develop new treatments by advancing mapping, profiling, and modeling of joint tissues and pain mechanisms.
This grant supports interdisciplinary research to understand how non-addictive natural products manage chronic pain through holistic, multisystem approaches, aiming to develop safe, evidence-based pain relief strategies.