Funder: National Institutes of Health

Due Dates: September 28, 2025 (Letter of Intent) | October 28, 2025 (Application) | November 24, 2025 (AIDS Application) | September 27, 2026 (Letter of Intent) | October 27, 2026 (Application) | November 23, 2026 (AIDS Application)

Funding Amounts: Up to $375,000 direct costs per project (max 3 years); no more than 1/3 to non-R15-eligible institutions.

Summary: Supports R15-eligible PIs to conduct basic/mechanistic pain research, foster interdisciplinary partnerships, and engage students in research.

Key Information: Requires a U.S. research partnership (subaward), strong student engagement, and strict eligibility; non-compliant applications will be withdrawn.