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    The Hoffman ALS Clinical Trial Awards Program

    Forecasted

    The Hoffman ALS Clinical Trial Awards Program supports researchers conducting early-stage trials of ALS treatments and imaging tracers to generate safety, dosing, and biomarker data for later development.

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    This grant was recently updated

    The updated text explicitly excludes observational studies, natural history studies, and expanded access protocol studies, with applications on these topics subject to administrative withdrawal. It also specifies that therapeutics must have completed or be completing IND-enabling studies by the full-proposal deadline.

    Hoffman ALS Clinic Development Awards

    The Hoffman ALS Clinic Development Awards from the ALS Association fund the creation and enhancement of multidisciplinary ALS clinics to expand access to high-quality, coordinated care.

    ALSADue Nov 4, 2026· 8d$900,000

    Hoffman ALS Clinic Capacity Awards

    The Hoffman ALS Clinic Capacity Awards from the ALS Association fund projects that expand multidisciplinary ALS care through increased clinic access and telemedicine.

    ALSADue Nov 4, 2026· 8d$360,000

    The Lawrence and Isabel Barnett Drug Development Program

    The Lawrence and Isabel Barnett Drug Development Program supports academic and industry investigators conducting preclinical studies of new or repurposed ALS therapies to advance them toward clinical testing.

    ALSADue Dec 8, 2026$500,000

    Award for Early Career Investigators in Clinical Studies in ALS

    Award for Early Career Investigators in Clinical Studies in ALS supports early career researchers conducting clinical studies in ALS, recognizing good research and encouraging their work in the field.

    AANForecasted Jan 1, 2028Forecasted

    Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

    This grant will fund research using data from expanded access to investigational drugs for ALS patients who are ineligible for clinical trials, aiming to improve prevention, diagnosis, or treatment of ALS.

    HHS-NIH11Due Nov 10, 2026· 14d$40,000,000